Ozone

Oxygen-ozone treatments offered for immune support and chronic inflammation. What they involve and why the questions below matter more than usual.

Researched and edited by Rob MartinezNot medically reviewed. No clinician has reviewed this page. Why that mattersLast updated 2026-09-17

Regulatory and evidence status

Ozone therapy is not FDA approved and evidence is limited and contested. Weigh any provider's claims carefully and ask for specifics.

What it is

Ozone therapy refers to a group of procedures that use a mixture of oxygen and ozone, delivered in several possible ways. Providers offer it for immune support and chronic inflammation, among other goals.

The FDA has not approved ozone therapy and has cautioned about certain uses. That does not tell you what any individual provider offers, but it does make transparency, method, and informed consent especially important. The questions below are where a careful provider stands out.

What providers commonly offer it for

  • Immune-support protocols
  • Chronic inflammation goals
  • Wellness and recovery programs

What a first visit usually involves

  1. A consultation about your goals and history.
  2. A clear explanation of the delivery method being proposed.
  3. The procedure, delivered as a session or a short course.
  4. Follow-up to review how you are responding.

Questions to ask a provider

  • How is the ozone delivered, and why that method?
  • How do you handle the fact that ozone therapy is not FDA approved?
  • What are the risks, and how do you obtain informed consent?
  • What evidence supports this for my specific goal?

Ozone: common questions

Is ozone therapy FDA approved?
No. The FDA has not approved ozone therapy and has cautioned about some uses. Ask any provider directly how they address that.
How is it delivered?
There are several methods. A provider should explain exactly which they use and why before proceeding.
What should I watch out for?
Be wary of strong claims, and look for clear informed consent and a frank discussion of risks. Credentials being checked is a starting point, not a substitute for these questions.

This page describes a treatment, not any one clinic's version of it, and it is information rather than medical advice. Read the editorial policy.